Melanocortin Research Peptides

Melanotan and melanocortin research peptides

Melanocortin peptides bind the MC1R–MC5R receptor family. Melanotan I (afamelanotide) is a relatively MC1R-selective α-MSH analogue studied in pigmentation research; Melanotan II is a cyclic, non-selective analogue; and KPV is the C-terminal tripeptide of α-MSH, studied for anti-inflammatory signalling in gut and skin models.

PT-141 (Bremelanotide), a related MC3R/MC4R agonist, is listed under Reproductive peptides.

Buying melanocortin research peptides

Each product lists its HPLC purity specification (≥98% or higher). Where a CertikLabs certificate of analysis (COA) is available for a strength and lot, it is linked from that product page with HPLC purity, LC-MS identity, and concentration results. Match the named analogue and sequence carefully: related melanocortins can differ in receptor selectivity and structure. For an evidence-based purchase review, use the research peptide supplier checklist, learn how peptide lab verification works, and confirm that any available report matches the ordered product, strength and lot. All compounds are supplied lyophilized, strictly for in-vitro laboratory research. They are not drugs, supplements or cosmetics and are not for human or veterinary use — see Research Use Only.

Frequently asked questions

What is the difference between Melanotan I and Melanotan II?

Melanotan I is a linear analogue that is relatively selective for MC1R; Melanotan II is a shorter cyclic analogue that binds several melanocortin receptors.