KPV (5mg)
Tiny But Powerful Anti-Inflammatory
Order KPV (5mg) online for laboratory research. Compare the listed vial options and current price, then add your selection to cart and continue to checkout. Review available COA records for the exact product, strength and lot. Research Use Only; not for human or veterinary use.
KPV (α-MSH 11-13) is listed for melanocortin laboratory research. Catalog vial contents are 5mg; select the required strength before ordering. This material is supplied for Research Use Only, not as a medicine or a product for human or veterinary use.
Research Applications & Benefits
- Potent NF-κB inhibitor
- Gut inflammation (IBD) research
- Antimicrobial properties
- Highly stable
What is KPV (α-MSH 11-13)?
Just three amino acids but remarkable NF-κB inhibition — the master inflammatory switch.
Listed vial contents: 5mg. These are supplied quantities, not administration doses. Current pricing and availability are shown in the strength selector.
What mechanisms are being studied?
KPV (Lys-Pro-Val) is the C-terminal tripeptide fragment of α-MSH. Despite being just three amino acids, it retains α-MSH's potent anti-inflammatory activity — primarily through direct inhibition of NF-κB nuclear translocation, the master transcriptional regulator of inflammation. It enters inflamed intestinal cells via the PepT1 transporter (upregulated in inflammation), creating a self-targeting system.
What are the research questions?
- Inflammatory bowel disease (IBD): The primary research focus. Studied extensively in ulcerative colitis and Crohn's disease models.
- Gut inflammation / leaky gut: Restores intestinal barrier integrity and reduces mucosal inflammation.
- Skin inflammation: Topical KPV studied for dermatitis, psoriasis, and wound healing.
- Antimicrobial: Direct antimicrobial activity against Staphylococcus aureus and Candida albicans.
What does the published work describe?
Brzoska T et al. (Endocr Rev 2008) — Comprehensive review of α-MSH/KPV anti-inflammatory mechanisms. Dalmasso G et al. (J Biol Chem 2008) — Oral KPV delivered via nanoparticles was as effective as injected anti-TNF antibodies in treating colitis in mice.
What are the limits of this evidence?
The research described concerns the cited experimental materials and models, not proof that this supplied vial is a treatment. Cell or animal findings do not establish human benefits. Clinical findings, where cited, apply to the tested formulation and population; they do not validate this research product for human use.
Study references
- Brzoska T et al. Endocr Rev 2008
- Dalmasso G et al. J Biol Chem 2008
These are the catalog's existing bibliographic references. No new source verification is implied by this presentation.
How should I check lot documentation?
Match the product, strength and lot to an original analysis document. Literature describes experimental findings; it does not verify the contents of this inventory. A report is evidence only for the product, strength and lot it names.
How is KPV (α-MSH 11-13) handled in the lab?
For KPV (α-MSH 11-13), record the product code KPV, selected strength and lot before opening. Follow the material-specific safety data sheet and laboratory SOP, with appropriate gloves, eye protection and containment. For a documented dry preparation, let the sealed vial equilibrate before opening to reduce condensation; minimize time open and use clean, compatible vessels.
Choose a solvent for KPV (α-MSH 11-13) from the documented sequence or chemical identity, salt form and assay requirements. Test a small portion first and record pH, solvent composition and clarity. Do not assume one diluent works for every research material; include a solvent-only control and establish compatibility before using the stock in an assay.
For KPV (α-MSH 11-13), calculate mass concentration as measured material mass divided by final solution volume. Calculate molarity only with a documented molecular weight for the supplied chemical form; no usable molecular weight is established by the blank catalog field. Where available, use matched-lot net content rather than treating chromatographic purity as a mass correction. Record both stock concentration and subsequent dilution factors.
Use the documented storage conditions for the supplied KPV (α-MSH 11-13) form and lot. For a documented lyophilized preparation, keep the vial sealed and protected from moisture; for solutions, validate temperature, light exposure and holding time in the assay. Use compatible single-use aliquots when appropriate to reduce repeated freeze-thaw. No universal temperature or 28-day solution shelf life is established by the catalog name.
A KPV (α-MSH 11-13) laboratory protocol should record identity, product code KPV, strength, lot, applicable analysis results, solvent and pH, stock concentration, dilution sequence, vessel type, storage history and assay endpoints. Include vehicle and reference controls, independent replicates and predefined acceptance criteria. Separate handling validation from biological interpretation; these notes do not provide administration or dosing instructions.
Research Use Only. Not for human consumption, therapeutic, veterinary or any in-vivo use.
Product Specifications
- Compound
- KPV (α-MSH 11-13)
- CAS Number
- 67727-97-3
- Molecular Weight
- HPLC Purity Specification
- ≥98%
- Category
- Melanocortin
- Starting Price
- $49.00 USD
- Country of Origin
- United States
- Shipping
- Cold-chain insulated packaging, fast domestic delivery
- Payment
- Card, ACH, and cryptocurrency (10% discount)
Quality & Verification
KPV (α-MSH 11-13) has a catalog purity specification of ≥98%; this is not a measured result for every vial. Match the product, exact strength, batch and lot to its analysis record and read only the reported fields. HPLC peak-area purity, measured content and endotoxin are separate measurements. A blank field means no result is reported, not zero or passed. A purity percentage alone does not establish identity, sterility or suitability for human use.
Frequently Asked Questions
What is KPV (α-MSH 11-13)?
KPV (α-MSH 11-13) is listed for melanocortin laboratory research. Catalog vial contents are 5mg; select the required strength before ordering. This material is supplied for Research Use Only, not as a medicine or a product for human or veterinary use.
What strengths of KPV (α-MSH 11-13) are available?
The catalog lists 5mg. These labels describe vial contents, not administration doses. Select the required strength for current pricing and availability; match analysis records to that exact strength and lot.
How should I interpret KPV (α-MSH 11-13) purity results?
KPV (α-MSH 11-13) has a catalog purity specification of ≥98%; this is not a measured result for every vial. Match the product, exact strength, batch and lot to its analysis record and read only the reported fields. HPLC peak-area purity, measured content and endotoxin are separate measurements. A blank field means no result is reported, not zero or passed. A purity percentage alone does not establish identity, sterility or suitability for human use.
How should KPV (α-MSH 11-13) be handled in the laboratory?
For KPV (α-MSH 11-13), record the product code KPV, selected strength and lot before opening. Follow the material-specific safety data sheet and laboratory SOP, with appropriate gloves, eye protection and containment. For a documented dry preparation, let the sealed vial equilibrate before opening to reduce condensation; minimize time open and use clean, compatible vessels.
How do I choose a laboratory solvent for KPV (α-MSH 11-13)?
Choose a solvent for KPV (α-MSH 11-13) from the documented sequence or chemical identity, salt form and assay requirements. Test a small portion first and record pH, solvent composition and clarity. Do not assume one diluent works for every research material; include a solvent-only control and establish compatibility before using the stock in an assay.
How do I calculate a KPV (α-MSH 11-13) stock concentration?
For KPV (α-MSH 11-13), calculate mass concentration as measured material mass divided by final solution volume. Calculate molarity only with a documented molecular weight for the supplied chemical form; no usable molecular weight is established by the blank catalog field. Where available, use matched-lot net content rather than treating chromatographic purity as a mass correction. Record both stock concentration and subsequent dilution factors.
How should KPV (α-MSH 11-13) be stored after preparation?
Use the documented storage conditions for the supplied KPV (α-MSH 11-13) form and lot. For a documented lyophilized preparation, keep the vial sealed and protected from moisture; for solutions, validate temperature, light exposure and holding time in the assay. Use compatible single-use aliquots when appropriate to reduce repeated freeze-thaw. No universal temperature or 28-day solution shelf life is established by the catalog name.
What should a KPV (α-MSH 11-13) lab protocol document?
A KPV (α-MSH 11-13) laboratory protocol should record identity, product code KPV, strength, lot, applicable analysis results, solvent and pH, stock concentration, dilution sequence, vessel type, storage history and assay endpoints. Include vehicle and reference controls, independent replicates and predefined acceptance criteria. Separate handling validation from biological interpretation; these notes do not provide administration or dosing instructions.
Does Fmoc or Boc synthesis explain this KPV (α-MSH 11-13) product?
Fmoc and Boc are peptide protecting-group strategies, not proof of how this KPV (α-MSH 11-13) lot was made. For sequence-defined peptides, synthesis review can examine deletion products, incomplete deprotection and modifications using the method and matching analytical evidence. A single chromatographic peak does not by itself establish sequence.
Is KPV (α-MSH 11-13) for human use?
No. KPV (α-MSH 11-13) is strictly Research Use Only. It is not intended for human or veterinary use, diagnosis or treatment. Laboratory handling guidance is not an administration protocol.
Research Use Only. This product is intended for licensed laboratory research and is not for human or veterinary use.
