Melanotan I (10mg)

Natural Tanning Peptide

Activates MC1R on melanocytes to increase eumelanin production.

Research Applications & Benefits

What is Melanotan I?

Activates MC1R on melanocytes to increase eumelanin production.

Listed vial contents: 10mg. These are supplied quantities, not administration doses. Current pricing and availability are shown in the strength selector.

What mechanisms are being studied?

Melanotan I (afamelanotide) is a 13-amino acid linear analog of α-MSH with enhanced selectivity for the MC1R receptor on melanocytes. MC1R activation stimulates eumelanin (brown/black protective pigment) synthesis via cAMP-PKA-MITF-tyrosinase signaling.

What are the research questions?

  • Erythropoietic protoporphyria (EPP): FDA-approved as Scenesse® (2019) for pain-free light exposure in EPP patients who otherwise cannot tolerate any sunlight.
  • Photoprotection research: Increases natural melanin production, potentially reducing UV damage and photoaging.
  • Vitiligo: Studied for repigmentation of depigmented skin patches.

What does the published work describe?

Langendonk JG et al. (NEJM 2015) — Scenesse® significantly increased pain-free sun exposure in EPP patients. FDA-approved with comprehensive safety and efficacy data. Measurable increase in skin melanin density confirmed.

What are the limits of this evidence?

The research described concerns the cited experimental materials and models, not proof that this supplied vial is a treatment. Cell or animal findings do not establish human benefits. Clinical findings, where cited, apply to the tested formulation and population; they do not validate this research product for human use.

Study references

  1. Langendonk JG et al. NEJM 2015

These are the catalog's existing bibliographic references. No new source verification is implied by this presentation.

How should I check lot documentation?

Match the product, strength and lot to an original analysis document. Literature describes experimental findings; it does not verify the contents of this inventory. Generated sample reports illustrate the reporting flow and are not evidence of testing, purity or accreditation.

Research Use Only. Not for human consumption, therapeutic, veterinary or any in-vivo use.

Product Specifications

Compound
Melanotan I
CAS Number
75921-69-6
Molecular Weight
1646.85 g/mol
HPLC Purity Specification
≥99%
Category
Melanocortin
Starting Price
$39.00 USD
Country of Origin
United States
Shipping
Cold-chain insulated packaging, fast domestic delivery
Payment
Card, ACH, and cryptocurrency (10% discount)

Quality & Verification

Melanotan I carries the purity specification shown above. Where a lot-specific CertikLabs Certificate of Analysis is available, the product page links its HPLC purity, LC-MS identity, and concentration results.

Frequently Asked Questions

Is Melanotan I suitable for human consumption?

No. Melanotan I is sold strictly for in-vitro laboratory research. It is not a drug, supplement, cosmetic, or food product and must not be administered to humans or animals.

What purity is Melanotan I?

Melanotan I carries a ≥99% HPLC purity specification. Check the product page for an available lot report.

How is Melanotan I shipped and stored?

Vials are shipped lyophilized in temperature-controlled packaging. Store unopened lyophilized peptide at −20°C; once reconstituted with bacteriostatic water, store at 2–8°C and use within 28 days.

Research Use Only. This product is intended for licensed laboratory research and is not for human or veterinary use.