NAD+ (100mg/750mg)

What is NAD+?

Participates in 500+ reactions, fuels sirtuins, required for DNA repair. Drops ~50% by age 60.

Listed vial contents: 100mg / 750mg. These are supplied quantities, not administration doses. Current pricing and availability are shown in the strength selector.

What mechanisms are being studied?

NAD+ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme participating in 500+ enzymatic reactions. It is the primary substrate for sirtuins (SIRT1-7), PARPs (DNA repair enzymes), and CD38 (immune signaling). NAD+ levels decline approximately 50% between ages 20-60.

What are the research questions?

• Age-related decline: Directly addresses the NAD+ deficit, restoring sirtuin activity and DNA repair capacity.
• Cognitive function / neurodegeneration: NAD+ is essential for neuronal health. Studied for neuroprotective effects in Alzheimer's and Parkinson's models.
• Metabolic health: Improves insulin sensitivity, mitochondrial function, and metabolic rate.
• Addiction recovery: IV NAD+ therapy is used by some clinics for addiction detoxification and withdrawal management.
• Athletic recovery: Supports cellular energy production and repair mechanisms.

What does the published work describe?

Imai S, Guarente L (Trends Cell Biol 2014) — Comprehensive review of NAD+ decline in aging. Harvard studies (Sinclair DA) — Restoring NAD+ reversed many markers of aging in mice. Human studies — 40-90% increase in blood NAD+ levels with supplementation.

What are the limits of this evidence?

The research described concerns the cited experimental materials and models, not proof that this supplied vial is a treatment. Cell or animal findings do not establish human benefits. Clinical findings, where cited, apply to the tested formulation and population; they do not validate this research product for human use.

Study references

1. Imai S, Guarente L. Trends Cell Biol 2014

These are the catalog's existing bibliographic references. No new source verification is implied by this presentation.

How should I check lot documentation?

Match the product, strength and lot to an original analysis document. Literature describes experimental findings; it does not verify the contents of this inventory. Generated sample reports illustrate the reporting flow and are not evidence of testing, purity or accreditation.