NAD+ Research Guide: is NAD+ a peptide?

NAD+ (nicotinamide adenine dinucleotide) is often sold alongside research peptides — many researchers search for "NAD+ peptide" — but it is not a peptide. It is a dinucleotide coenzyme found in every living cell, central to energy metabolism and used by enzymes such as sirtuins and PARPs. Animal studies report that NAD+ levels fall with age, which is why NAD+ research is a major focus of aging science. Supplied here as ≥99% purity lyophilised powder for laboratory research use only.

Specifications

Compound classDinucleotide coenzyme (not a peptide)
CAS number53-84-9
Molecular weight663.43 g/mol
Purity≥99% (HPLC)
FormLyophilised powder

Why people search "NAD+ peptide"

NAD+ is stocked by peptide suppliers because it is handled the same way — supplied as a lyophilised powder and reconstituted in the lab. Chemically it is two nucleotides joined by a phosphate bridge, with no amino acids at all.

What NAD+ does in cells

NAD+ carries electrons in the reactions that turn nutrients into cellular energy. It is also consumed as a substrate by sirtuins and PARP enzymes, which link it to DNA repair and cellular stress responses (Verdin, 2015).

Published research

A 2018 review in Cell Metabolism summarised in-vivo evidence that raising NAD+ levels — mostly through precursors such as nicotinamide riboside and nicotinamide mononucleotide — affects metabolic and age-related measures in animal models (Rajman et al., 2018).

Frequently asked questions

Is NAD+ a peptide?

No. NAD+ is a dinucleotide coenzyme. It is sold by peptide suppliers because it is supplied and handled in the same lyophilised format.

Why is NAD+ studied in aging research?

Animal studies report that NAD+ levels decline with age, and NAD+ is required by sirtuins and PARPs involved in DNA repair and stress responses.

How should NAD+ be stored?

Keep lyophilised NAD+ cold, dry and protected from light; refrigerate reconstituted solutions.

What NAD+ sizes are available?

PeptidesDirect supplies NAD+ in 100mg and 750mg vials for laboratory research only. See our research peptides guide (/learn/research-peptides) for how to compare suppliers and read test documents.

Is NAD+ the same as NMN?

No. NMN is a precursor that cells convert into NAD+; they are different molecules. See our research peptides guide (/learn/research-peptides) for how to compare suppliers and read test documents.

Is this product for human use?

No. PeptidesDirect sells this compound for laboratory research only. It is not a drug, food or cosmetic and is not for human or veterinary use. This page summarises published research and is not dosing or medical guidance.

References

  1. Verdin E. NAD+ in aging, metabolism, and neurodegeneration. Science. 2015. PubMed 26785480
  2. Rajman L, et al. Therapeutic potential of NAD-boosting molecules: the in vivo evidence. Cell Metab. 2018. PubMed 29514064

Research compounds

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Research Use Only. Not for human or veterinary use. Not dosing or medical guidance.