Semax (25mg)

What is Semax?

Increases BDNF — promoting new neural connections, protecting neurons, and enhancing learning.

Listed vial contents: 25mg. These are supplied quantities, not administration doses. Current pricing and availability are shown in the strength selector.

What mechanisms are being studied?

Semax is a synthetic heptapeptide derived from the ACTH(4-10) fragment, with a Pro-Gly-Pro C-terminal extension for metabolic stability. It increases brain-derived neurotrophic factor (BDNF) expression 1.5-3x, promoting neurogenesis, synaptic plasticity, and neuroprotection. It also modulates dopamine, serotonin, and acetylcholine neurotransmission. Administered intranasally for direct CNS delivery.

What are the research questions?

• Stroke recovery: Prescribed in Russia for over 25 years for acute ischemic stroke — reduced infarct volume by 25-40% when administered within 6 hours.
• Cognitive enhancement: Improves attention, memory formation, and learning capacity through BDNF upregulation.
• Optic nerve atrophy: Approved in Russia for treatment of optic nerve diseases — improved visual acuity and visual field.
• ADHD: Studied as an adjunct therapy for attention deficit disorders.
• Neuroprotection: Protective against oxidative stress, excitotoxicity, and traumatic brain injury.

What does the published work describe?

Dolotov OV et al. (Neuroscience 2006) — 1.5-3x BDNF increase confirmed. Prescribed in Russia/CIS since ~1995 for stroke, cognitive impairment, and optic nerve atrophy. Eremin KO et al. — Reduced infarct size 25-40% in stroke models.

What are the limits of this evidence?

The research described concerns the cited experimental materials and models, not proof that this supplied vial is a treatment. Cell or animal findings do not establish human benefits. Clinical findings, where cited, apply to the tested formulation and population; they do not validate this research product for human use.

Study references

1. Dolotov OV et al. Neuroscience 2006

These are the catalog's existing bibliographic references. No new source verification is implied by this presentation.

How should I check lot documentation?

Match the product, strength and lot to an original analysis document. Literature describes experimental findings; it does not verify the contents of this inventory. Generated sample reports illustrate the reporting flow and are not evidence of testing, purity or accreditation.