PT-141 (10mg)

What is PT-141 (Bremelanotide)?

Works in the brain, not blood vessels — activating MC4R in the hypothalamus.

Listed vial contents: 10mg. These are supplied quantities, not administration doses. Current pricing and availability are shown in the strength selector.

What mechanisms are being studied?

PT-141 (Bremelanotide) is a cyclic heptapeptide melanocortin receptor agonist that primarily targets MC4R and MC3R in the hypothalamus. Unlike PDE5 inhibitors (Viagra/Cialis) which act on blood vessels, PT-141 works centrally in the brain to modulate sexual arousal pathways.

What are the research questions?

• Hypoactive Sexual Desire Disorder (HSDD): FDA-approved as Vyleesi® (2019) for premenopausal women with acquired, generalized HSDD.
• Erectile dysfunction (male): Phase 2/3 data showed efficacy in ED, including in patients who failed PDE5 inhibitors.
• Sexual dysfunction research: Unique mechanism of action (brain-based vs vascular) makes it valuable for studying central sexual arousal pathways.

What does the published work describe?

Kingsberg SA et al. (Obstet Gynecol 2019) — RECONNECT trial: Statistically significant improvement in sexual desire and associated distress. Diamond LE et al. (Int J Impot Res 2004) — Phase 2 ED trial: 67% erection response vs 32% placebo, including 33% response in PDE5 non-responders.

What are the limits of this evidence?

The research described concerns the cited experimental materials and models, not proof that this supplied vial is a treatment. Cell or animal findings do not establish human benefits. Clinical findings, where cited, apply to the tested formulation and population; they do not validate this research product for human use.

Study references

1. Kingsberg SA et al. Obstet Gynecol 2019
2. Diamond LE et al. Int J Impot Res 2004

These are the catalog's existing bibliographic references. No new source verification is implied by this presentation.

How should I check lot documentation?

Match the product, strength and lot to an original analysis document. Literature describes experimental findings; it does not verify the contents of this inventory. Generated sample reports illustrate the reporting flow and are not evidence of testing, purity or accreditation.