Pemvidutide (10mg)
Balanced GLP-1 / Glucagon Dual Agonist for MASH & Obesity
Pemvidutide is listed for GLP-1 and glucagon research. Catalog vial contents are 10mg; select the required strength before ordering. This material is supplied for Research Use Only, not as a medicine or a product for human or veterinary use.
Research Applications & Benefits
- Balanced 1:1 GLP-1 / glucagon dual agonism
- Glucagon-driven energy expenditure mechanism
- Direct hepatic fat-reduction signaling
- Active MASH and obesity research programs
What is Pemvidutide?
Pemvidutide, also called ALT-801, is a peptide studied at GLP-1 and glucagon receptors. This catalog lists a 10mg research vial. Receptor activity and liver-related clinical endpoints are different kinds of evidence.
Listed vial contents: 10mg. These are supplied quantities, not administration doses. Current pricing and availability are shown in the strength selector.
What mechanisms are being studied?
Dual agonism allows researchers to examine GLP-1 and glucagon signaling in metabolic models. Liver fat measurements, tissue findings and receptor assays answer different questions and should not be treated as interchangeable.
What are the research questions?
- GLP-1 and glucagon signaling
- Distinguishing liver fat from inflammation and fibrosis endpoints
- Formulation-specific metabolic research
What does the published work describe?
The 2025 IMPACT paper reports 24-week results from a randomized phase 2b trial in adults with biopsy-confirmed metabolic dysfunction-associated steatohepatitis and liver fibrosis. MASH is a liver condition involving fat accumulation and inflammation. The trial studied a defined clinical formulation, not this reagent.
Experimental models in the cited papers
- IMPACT: randomized, double-blind phase 2b human MASH trial
What could future research explore?
Future research can examine how receptor responses relate to distinct liver endpoints. Evidence about tissue inflammation does not automatically establish an effect on fibrosis or predict an outcome in another population.
These are research directions, not established applications of the product sold here.
What are the limits of this evidence?
Clinical findings apply to the tested formulation, trial population and study conditions. They do not establish the identity, safety or effectiveness of this laboratory vial. Research Use Only: this material is not a finished medicine.
Study references
- Noureddin M, et al. Safety and efficacy of weekly pemvidutide versus placebo for metabolic dysfunction-associated steatohepatitis (IMPACT): 24-week results from a multicentre, randomised, double-blind, phase 2b study. Lancet. 2025. PMID 41237796
How should I check lot documentation?
Match the product, strength and lot to an original analysis document. Literature describes experimental findings; it does not verify the contents of this inventory. A report is evidence only for the product, strength and lot it names.
How is Pemvidutide handled in the lab?
For Pemvidutide, record the product code PEMV-10, selected strength and lot before opening. Follow the material-specific safety data sheet and laboratory SOP, with appropriate gloves, eye protection and containment. For a documented dry preparation, let the sealed vial equilibrate before opening to reduce condensation; minimize time open and use clean, compatible vessels.
Choose a solvent for Pemvidutide from the documented sequence or chemical identity, salt form and assay requirements. Test a small portion first and record pH, solvent composition and clarity. Do not assume one diluent works for every research material; include a solvent-only control and establish compatibility before using the stock in an assay. For a documented lipid-modified construct, evaluate aggregation and adsorption as well as apparent solubility; check compatibility again after dilution into the final assay buffer.
For Pemvidutide, calculate mass concentration as measured material mass divided by final solution volume. Calculate molarity only with a documented molecular weight for the supplied chemical form; the catalog lists ~4900 g/mol as a reference, not lot confirmation. Where available, use matched-lot net content rather than treating chromatographic purity as a mass correction. Record both stock concentration and subsequent dilution factors.
Use the documented storage conditions for the supplied Pemvidutide form and lot. For a documented lyophilized preparation, keep the vial sealed and protected from moisture; for solutions, validate temperature, light exposure and holding time in the assay. Use compatible single-use aliquots when appropriate to reduce repeated freeze-thaw. No universal temperature or 28-day solution shelf life is established by the catalog name.
A Pemvidutide laboratory protocol should record identity, product code PEMV-10, strength, lot, applicable analysis results, solvent and pH, stock concentration, dilution sequence, vessel type, storage history and assay endpoints. Include vehicle and reference controls, independent replicates and predefined acceptance criteria. Separate handling validation from biological interpretation; these notes do not provide administration or dosing instructions.
Research Use Only. Not for human consumption, therapeutic, veterinary or any in-vivo use.
Product Specifications
- Compound
- Pemvidutide
- CAS Number
- 2243178-09-2
- Molecular Weight
- ~4900 g/mol
- HPLC Purity Specification
- ≥99%
- Category
- GLP-1 & Metabolic
- Starting Price
- $239.00 USD
- Country of Origin
- United States
- Shipping
- Cold-chain insulated packaging, fast domestic delivery
- Payment
- Card, ACH, and cryptocurrency (10% discount)
Quality & Verification
Pemvidutide has a catalog purity specification of ≥99%; this is not a measured result for every vial. Match the product, exact strength, batch and lot to its analysis record and read only the reported fields. HPLC peak-area purity, measured content and endotoxin are separate measurements. A blank field means no result is reported, not zero or passed. A purity percentage alone does not establish identity, sterility or suitability for human use.
Frequently Asked Questions
What is Pemvidutide?
Pemvidutide is listed for GLP-1 and glucagon research. Catalog vial contents are 10mg; select the required strength before ordering. This material is supplied for Research Use Only, not as a medicine or a product for human or veterinary use.
What strengths of Pemvidutide are available?
The catalog lists 10mg. These labels describe vial contents, not administration doses. Select the required strength for current pricing and availability; match analysis records to that exact strength and lot.
How should I interpret Pemvidutide purity results?
Pemvidutide has a catalog purity specification of ≥99%; this is not a measured result for every vial. Match the product, exact strength, batch and lot to its analysis record and read only the reported fields. HPLC peak-area purity, measured content and endotoxin are separate measurements. A blank field means no result is reported, not zero or passed. A purity percentage alone does not establish identity, sterility or suitability for human use.
How should Pemvidutide be handled in the laboratory?
For Pemvidutide, record the product code PEMV-10, selected strength and lot before opening. Follow the material-specific safety data sheet and laboratory SOP, with appropriate gloves, eye protection and containment. For a documented dry preparation, let the sealed vial equilibrate before opening to reduce condensation; minimize time open and use clean, compatible vessels.
How do I choose a laboratory solvent for Pemvidutide?
Choose a solvent for Pemvidutide from the documented sequence or chemical identity, salt form and assay requirements. Test a small portion first and record pH, solvent composition and clarity. Do not assume one diluent works for every research material; include a solvent-only control and establish compatibility before using the stock in an assay. For a documented lipid-modified construct, evaluate aggregation and adsorption as well as apparent solubility; check compatibility again after dilution into the final assay buffer.
How do I calculate a Pemvidutide stock concentration?
For Pemvidutide, calculate mass concentration as measured material mass divided by final solution volume. Calculate molarity only with a documented molecular weight for the supplied chemical form; the catalog lists ~4900 g/mol as a reference, not lot confirmation. Where available, use matched-lot net content rather than treating chromatographic purity as a mass correction. Record both stock concentration and subsequent dilution factors.
How should Pemvidutide be stored after preparation?
Use the documented storage conditions for the supplied Pemvidutide form and lot. For a documented lyophilized preparation, keep the vial sealed and protected from moisture; for solutions, validate temperature, light exposure and holding time in the assay. Use compatible single-use aliquots when appropriate to reduce repeated freeze-thaw. No universal temperature or 28-day solution shelf life is established by the catalog name.
What should a Pemvidutide lab protocol document?
A Pemvidutide laboratory protocol should record identity, product code PEMV-10, strength, lot, applicable analysis results, solvent and pH, stock concentration, dilution sequence, vessel type, storage history and assay endpoints. Include vehicle and reference controls, independent replicates and predefined acceptance criteria. Separate handling validation from biological interpretation; these notes do not provide administration or dosing instructions.
Does Fmoc or Boc synthesis explain this Pemvidutide product?
Fmoc and Boc are peptide protecting-group strategies, not proof of how this Pemvidutide lot was made. For sequence-defined peptides, synthesis review can examine deletion products, incomplete deprotection and modifications using the method and matching analytical evidence. A single chromatographic peak does not by itself establish sequence.
Is Pemvidutide for human use?
No. Pemvidutide is strictly Research Use Only. It is not intended for human or veterinary use, diagnosis or treatment. Laboratory handling guidance is not an administration protocol.
Research Use Only. This product is intended for licensed laboratory research and is not for human or veterinary use.
