P21 (5mg)
Next-Gen Neurogenesis Compound
Promotes new neuron growth in hippocampus and inhibits tau phosphorylation.
Research Applications & Benefits
- Promotes neurogenesis
- Inhibits tau phosphorylation
- Targets hippocampus
- Novel mechanism
What is P21 (P021)?
Promotes new neuron growth in hippocampus and inhibits tau phosphorylation.
Listed vial contents: 5mg. These are supplied quantities, not administration doses. Current pricing and availability are shown in the strength selector.
What mechanisms are being studied?
P21 is an 11-amino acid peptide derived from the active region of ciliary neurotrophic factor (CNTF), modified with adamantylated amino acids to enable blood-brain barrier penetration and oral bioavailability. It promotes neurogenesis specifically in the hippocampus, inhibits leukemia inhibitory factor (LIF) signaling to reduce tau hyperphosphorylation, and increases BDNF expression by 30-50%.
What are the research questions?
- Alzheimer's disease research: Addresses two core pathologies simultaneously — promoting neurogenesis and inhibiting tau phosphorylation.
- Cognitive decline / neurodegeneration: Hippocampal neurogenesis supports new memory formation and spatial navigation.
- Traumatic brain injury: Neurogenic and neurotrophic effects may support recovery from brain injury.
What does the published work describe?
Bolognin S et al. (Neurobiol Aging 2014) — Improved spatial memory, increased hippocampal neurogenesis, and reduced tau phosphorylation in Alzheimer's mouse models. BDNF increase of 30-50% confirmed.
What are the limits of this evidence?
The research described concerns the cited experimental materials and models, not proof that this supplied vial is a treatment. Cell or animal findings do not establish human benefits. Clinical findings, where cited, apply to the tested formulation and population; they do not validate this research product for human use.
Study references
- Bolognin S et al. Neurobiol Aging 2014
These are the catalog's existing bibliographic references. No new source verification is implied by this presentation.
How should I check lot documentation?
Match the product, strength and lot to an original analysis document. Literature describes experimental findings; it does not verify the contents of this inventory. Generated sample reports illustrate the reporting flow and are not evidence of testing, purity or accreditation.
Research Use Only. Not for human consumption, therapeutic, veterinary or any in-vivo use.
Product Specifications
- Compound
- P21 (P021)
- CAS Number
- Molecular Weight
- HPLC Purity Specification
- ≥98%
- Category
- Cognitive
- Starting Price
- $79.00 USD
- Country of Origin
- United States
- Shipping
- Cold-chain insulated packaging, fast domestic delivery
- Payment
- Card, ACH, and cryptocurrency (10% discount)
Quality & Verification
P21 (P021) carries the purity specification shown above. Where a lot-specific CertikLabs Certificate of Analysis is available, the product page links its HPLC purity, LC-MS identity, and concentration results.
Frequently Asked Questions
Is P21 (P021) suitable for human consumption?
No. P21 (P021) is sold strictly for in-vitro laboratory research. It is not a drug, supplement, cosmetic, or food product and must not be administered to humans or animals.
What purity is P21 (P021)?
P21 (P021) carries a ≥98% HPLC purity specification. Check the product page for an available lot report.
How is P21 (P021) shipped and stored?
Vials are shipped lyophilized in temperature-controlled packaging. Store unopened lyophilized peptide at −20°C; once reconstituted with bacteriostatic water, store at 2–8°C and use within 28 days.
Research Use Only. This product is intended for licensed laboratory research and is not for human or veterinary use.
