Matrixyl (10mg)

What is Matrixyl (Palmitoyl Pentapeptide-4)?

A palmitoylated pentapeptide derived from procollagen I that upregulates extracellular-matrix protein synthesis in fibroblast cultures.

Listed vial contents: 10mg. These are supplied quantities, not administration doses. Current pricing and availability are shown in the strength selector.

What mechanisms are being studied?

Matrixyl (Pal-KTTKS) is a palmitoyl-conjugated pentapeptide derived from the C-terminus of Type I procollagen. The KTTKS sequence is a fragment released during collagen synthesis that signals fibroblasts via a feedback loop to produce more collagen and glycosaminoglycans. The palmitoyl tail increases lipid solubility and percutaneous delivery.

What are the research questions?

• Skin-aging research: Stimulates Type I and III collagen, fibronectin, and GAG production in dermal fibroblast cultures.
• Wound-healing models: Accelerated re-epithelialization in cultured keratinocyte assays.
• Comparator in topical peptide research: Reference compound for matrikine biology.

What does the published work describe?

Robinson LR et al. (Int J Cosmet Sci 2005) — improved wrinkle appearance vs vehicle at 12 weeks in a double-blinded study. Lintner K. — established collagen-upregulation profile in fibroblast cultures.

What are the limits of this evidence?

The research described concerns the cited experimental materials and models, not proof that this supplied vial is a treatment. Cell or animal findings do not establish human benefits. Clinical findings, where cited, apply to the tested formulation and population; they do not validate this research product for human use.

Study references

1. Robinson LR et al. Int J Cosmet Sci 2005
2. Lintner K. Cosmet Toiletries 2002

These are the catalog's existing bibliographic references. No new source verification is implied by this presentation.

How should I check lot documentation?

Match the product, strength and lot to an original analysis document. Literature describes experimental findings; it does not verify the contents of this inventory. A report is evidence only for the product, strength and lot it names.

How is Matrixyl (Palmitoyl Pentapeptide-4) handled in the lab?

Plan a Matrixyl (Palmitoyl Pentapeptide-4) stock solution from the sequence, the listed molecular weight (802.10 g/mol) and, when reported for the same lot, net peptide content. Test-dissolve a small portion first, store the powder sealed, cold and dry, and split solutions into single-use aliquots. These are laboratory handling notes, not administration guidance.

• Peptide solubility: choosing a lab solvent
• Stock solution molarity and concentration math
• Lyophilized storage, aliquoting and freeze-thaw
• Fmoc vs Boc synthesis and the impurities they leave