Mazdutide (5mg/10mg)
GLP-1 / Glucagon Dual Agonist — Innovent IBI362
A long-acting GLP-1/glucagon dual agonist derived from oxyntomodulin, in late-stage development for obesity and type 2 diabetes.
Research Applications & Benefits
- Oxyntomodulin-based dual agonism
- Significant weight and HbA1c reduction
- Favorable lipid profile data
- Once-weekly dosing
What is Mazdutide?
Mazdutide, also called IBI362 or LY3305677, is a GLP-1 and glucagon receptor dual agonist. It is distinct from ecnoglutide. The catalog lists 5mg and 10mg research vials.
Listed vial contents: 5mg / 10mg. These are supplied quantities, not administration doses. Current pricing and availability are shown in the strength selector.
What mechanisms are being studied?
Mazdutide is an analogue of oxyntomodulin, a hormone with GLP-1 and glucagon receptor activity. Researchers study receptor activation and the effects of structural modifications. A receptor mechanism does not establish the outcome of a particular experiment.
What are the research questions?
- Oxyntomodulin-related receptor pharmacology
- GLP-1 versus glucagon signaling
- Distinguishing early clinical characterization from analytical vial identity
What does the published work describe?
Ji and colleagues' 2021 phase 1b study evaluated IBI362 in Chinese adults with overweight or obesity. This randomized placebo-controlled study investigated safety, tolerability and pharmacokinetics. Pharmacokinetics describes how a tested material behaves in the body; it does not certify this laboratory reagent.
Experimental models in the cited papers
- Randomized placebo-controlled phase 1b human trial; Chinese adults with overweight or obesity
What could future research explore?
Further work can compare dual-receptor signaling in controlled assays and examine how formulation changes affect behavior. Clinical development questions require the actual tested formulation and appropriate study populations.
These are research directions, not established applications of the product sold here.
What are the limits of this evidence?
Clinical findings apply to the tested formulation, trial population and study conditions. They do not establish the identity, safety or effectiveness of this laboratory vial. Research Use Only: this material is not a finished medicine.
Study references
- Ji L, et al. IBI362 (LY3305677), a weekly-dose GLP-1 and glucagon receptor dual agonist, in Chinese adults with overweight or obesity: A randomised, placebo-controlled, multiple ascending dose phase 1b study. EClinicalMedicine. 2021. PMID 34430840
How should I check lot documentation?
Match the product, strength and lot to an original analysis document. Literature describes experimental findings; it does not verify the contents of this inventory. A report is evidence only for the product, strength and lot it names.
How is Mazdutide handled in the lab?
Plan a Mazdutide stock solution from the sequence, the listed molecular weight (4366.79 g/mol) and, when reported for the same lot, net peptide content. Test-dissolve a small portion first, store the powder sealed, cold and dry, and split solutions into single-use aliquots. These are laboratory handling notes, not administration guidance.
Research Use Only. Not for human consumption, therapeutic, veterinary or any in-vivo use.
Product Specifications
- Compound
- Mazdutide
- CAS Number
- 2259378-13-9
- Molecular Weight
- 4366.79 g/mol
- HPLC Purity Specification
- ≥98%
- Category
- GLP-1 & Metabolic
- Starting Price
- $99.00 USD
- Country of Origin
- United States
- Shipping
- Cold-chain insulated packaging, fast domestic delivery
- Payment
- Card, ACH, and cryptocurrency (10% discount)
Quality & Verification
Mazdutide carries the purity specification shown above. Where a lot-specific CertikLabs Certificate of Analysis is available, the product page links its HPLC purity, LC-MS identity, and concentration results.
Frequently Asked Questions
Is Mazdutide suitable for human consumption?
No. Mazdutide is sold strictly for in-vitro laboratory research. It is not a drug, supplement, cosmetic, or food product and must not be administered to humans or animals.
What purity is Mazdutide?
Mazdutide carries a ≥98% HPLC purity specification. Check the product page for an available lot report.
How is Mazdutide shipped and stored?
Vials are shipped lyophilized in temperature-controlled packaging. Store unopened lyophilized peptide at −20°C; once reconstituted with bacteriostatic water, store at 2–8°C and use within 28 days.
Research Use Only. This product is intended for licensed laboratory research and is not for human or veterinary use.
