LL-37 (5mg)

Your Body's Own Antibiotic Peptide

Order LL-37 (5mg) online for laboratory research. Compare the listed vial options and current price, then add your selection to cart and continue to checkout. Review available COA records for the exact product, strength and lot. Research Use Only; not for human or veterinary use.

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LL-37 (CAP-18) is listed for immune laboratory research. Catalog vial contents are 5mg; select the required strength before ordering. This material is supplied for Research Use Only, not as a medicine or a product for human or veterinary use.

Research Applications & Benefits

What is LL-37 (CAP-18)?

The only human cathelicidin — directly kills bacteria, viruses, and fungi.

Listed vial contents: 5mg. These are supplied quantities, not administration doses. Current pricing and availability are shown in the strength selector.

What mechanisms are being studied?

LL-37 is a 37-amino acid amphipathic alpha-helical peptide — the only human cathelicidin antimicrobial peptide. It permeabilizes microbial membranes through electrostatic interactions, creating pores that destroy bacteria, viruses, fungi, and biofilms. It also recruits immune cells, promotes wound healing through angiogenesis, and modulates inflammatory responses.

What are the research questions?

  • Antimicrobial defense: Broad-spectrum activity against bacteria (including MRSA and VRE), viruses, and fungi.
  • Biofilm disruption: Disrupts established biofilms — critical for chronic infections where biofilm-dwelling bacteria resist conventional antibiotics.
  • Wound healing: Promotes wound closure 30-50% faster through combined antimicrobial and tissue repair mechanisms.
  • Chronic infections: Studied for management of infections resistant to conventional antibiotic therapy.
  • Immune modulation: Bridges innate and adaptive immunity; recruits and activates neutrophils, monocytes, and T-cells.

What does the published work describe?

Vandamme D et al. (Cell Immunol 2012) — Comprehensive review of antimicrobial, immunomodulatory, and wound healing properties. Activity confirmed against MRSA, VRE, Pseudomonas aeruginosa, Candida. Wound healing: 30-50% faster closure. Overhage J et al. — Biofilm disruption against Pseudomonas aeruginosa.

What are the limits of this evidence?

The research described concerns the cited experimental materials and models, not proof that this supplied vial is a treatment. Cell or animal findings do not establish human benefits. Clinical findings, where cited, apply to the tested formulation and population; they do not validate this research product for human use.

Study references

  1. Vandamme D et al. Cell Immunol 2012

These are the catalog's existing bibliographic references. No new source verification is implied by this presentation.

How should I check lot documentation?

Match the product, strength and lot to an original analysis document. Literature describes experimental findings; it does not verify the contents of this inventory. A report is evidence only for the product, strength and lot it names.

How is LL-37 (CAP-18) handled in the lab?

For LL-37 (CAP-18), record the product code LL37, selected strength and lot before opening. Follow the material-specific safety data sheet and laboratory SOP, with appropriate gloves, eye protection and containment. For a documented dry preparation, let the sealed vial equilibrate before opening to reduce condensation; minimize time open and use clean, compatible vessels.

Choose a solvent for LL-37 (CAP-18) from the documented sequence or chemical identity, salt form and assay requirements. Test a small portion first and record pH, solvent composition and clarity. Do not assume one diluent works for every research material; include a solvent-only control and establish compatibility before using the stock in an assay.

For LL-37 (CAP-18), calculate mass concentration as measured material mass divided by final solution volume. Calculate molarity only with a documented molecular weight for the supplied chemical form; no usable molecular weight is established by the blank catalog field. Where available, use matched-lot net content rather than treating chromatographic purity as a mass correction. Record both stock concentration and subsequent dilution factors.

Use the documented storage conditions for the supplied LL-37 (CAP-18) form and lot. For a documented lyophilized preparation, keep the vial sealed and protected from moisture; for solutions, validate temperature, light exposure and holding time in the assay. Use compatible single-use aliquots when appropriate to reduce repeated freeze-thaw. No universal temperature or 28-day solution shelf life is established by the catalog name.

A LL-37 (CAP-18) laboratory protocol should record identity, product code LL37, strength, lot, applicable analysis results, solvent and pH, stock concentration, dilution sequence, vessel type, storage history and assay endpoints. Include vehicle and reference controls, independent replicates and predefined acceptance criteria. Separate handling validation from biological interpretation; these notes do not provide administration or dosing instructions.

Research Use Only. Not for human consumption, therapeutic, veterinary or any in-vivo use.

Product Specifications

Compound
LL-37 (CAP-18)
CAS Number
154947-66-7
Molecular Weight
HPLC Purity Specification
≥98%
Category
Immune
Starting Price
$59.00 USD
Country of Origin
United States
Shipping
Cold-chain insulated packaging, fast domestic delivery
Payment
Card, ACH, and cryptocurrency (10% discount)

Quality & Verification

LL-37 (CAP-18) has a catalog purity specification of ≥98%; this is not a measured result for every vial. Match the product, exact strength, batch and lot to its analysis record and read only the reported fields. HPLC peak-area purity, measured content and endotoxin are separate measurements. A blank field means no result is reported, not zero or passed. A purity percentage alone does not establish identity, sterility or suitability for human use.

Frequently Asked Questions

What is LL-37 (CAP-18)?

LL-37 (CAP-18) is listed for immune laboratory research. Catalog vial contents are 5mg; select the required strength before ordering. This material is supplied for Research Use Only, not as a medicine or a product for human or veterinary use.

What strengths of LL-37 (CAP-18) are available?

The catalog lists 5mg. These labels describe vial contents, not administration doses. Select the required strength for current pricing and availability; match analysis records to that exact strength and lot.

How should I interpret LL-37 (CAP-18) purity results?

LL-37 (CAP-18) has a catalog purity specification of ≥98%; this is not a measured result for every vial. Match the product, exact strength, batch and lot to its analysis record and read only the reported fields. HPLC peak-area purity, measured content and endotoxin are separate measurements. A blank field means no result is reported, not zero or passed. A purity percentage alone does not establish identity, sterility or suitability for human use.

How should LL-37 (CAP-18) be handled in the laboratory?

For LL-37 (CAP-18), record the product code LL37, selected strength and lot before opening. Follow the material-specific safety data sheet and laboratory SOP, with appropriate gloves, eye protection and containment. For a documented dry preparation, let the sealed vial equilibrate before opening to reduce condensation; minimize time open and use clean, compatible vessels.

How do I choose a laboratory solvent for LL-37 (CAP-18)?

Choose a solvent for LL-37 (CAP-18) from the documented sequence or chemical identity, salt form and assay requirements. Test a small portion first and record pH, solvent composition and clarity. Do not assume one diluent works for every research material; include a solvent-only control and establish compatibility before using the stock in an assay.

How do I calculate a LL-37 (CAP-18) stock concentration?

For LL-37 (CAP-18), calculate mass concentration as measured material mass divided by final solution volume. Calculate molarity only with a documented molecular weight for the supplied chemical form; no usable molecular weight is established by the blank catalog field. Where available, use matched-lot net content rather than treating chromatographic purity as a mass correction. Record both stock concentration and subsequent dilution factors.

How should LL-37 (CAP-18) be stored after preparation?

Use the documented storage conditions for the supplied LL-37 (CAP-18) form and lot. For a documented lyophilized preparation, keep the vial sealed and protected from moisture; for solutions, validate temperature, light exposure and holding time in the assay. Use compatible single-use aliquots when appropriate to reduce repeated freeze-thaw. No universal temperature or 28-day solution shelf life is established by the catalog name.

What should a LL-37 (CAP-18) lab protocol document?

A LL-37 (CAP-18) laboratory protocol should record identity, product code LL37, strength, lot, applicable analysis results, solvent and pH, stock concentration, dilution sequence, vessel type, storage history and assay endpoints. Include vehicle and reference controls, independent replicates and predefined acceptance criteria. Separate handling validation from biological interpretation; these notes do not provide administration or dosing instructions.

Does Fmoc or Boc synthesis explain this LL-37 (CAP-18) product?

Fmoc and Boc are peptide protecting-group strategies, not proof of how this LL-37 (CAP-18) lot was made. For sequence-defined peptides, synthesis review can examine deletion products, incomplete deprotection and modifications using the method and matching analytical evidence. A single chromatographic peak does not by itself establish sequence.

Is LL-37 (CAP-18) for human use?

No. LL-37 (CAP-18) is strictly Research Use Only. It is not intended for human or veterinary use, diagnosis or treatment. Laboratory handling guidance is not an administration protocol.

Research Use Only. This product is intended for licensed laboratory research and is not for human or veterinary use.