LL-37 (5mg)

What is LL-37 (CAP-18)?

The only human cathelicidin — directly kills bacteria, viruses, and fungi.

Listed vial contents: 5mg. These are supplied quantities, not administration doses. Current pricing and availability are shown in the strength selector.

What mechanisms are being studied?

LL-37 is a 37-amino acid amphipathic alpha-helical peptide — the only human cathelicidin antimicrobial peptide. It permeabilizes microbial membranes through electrostatic interactions, creating pores that destroy bacteria, viruses, fungi, and biofilms. It also recruits immune cells, promotes wound healing through angiogenesis, and modulates inflammatory responses.

What are the research questions?

• Antimicrobial defense: Broad-spectrum activity against bacteria (including MRSA and VRE), viruses, and fungi.
• Biofilm disruption: Disrupts established biofilms — critical for chronic infections where biofilm-dwelling bacteria resist conventional antibiotics.
• Wound healing: Promotes wound closure 30-50% faster through combined antimicrobial and tissue repair mechanisms.
• Chronic infections: Studied for management of infections resistant to conventional antibiotic therapy.
• Immune modulation: Bridges innate and adaptive immunity; recruits and activates neutrophils, monocytes, and T-cells.

What does the published work describe?

Vandamme D et al. (Cell Immunol 2012) — Comprehensive review of antimicrobial, immunomodulatory, and wound healing properties. Activity confirmed against MRSA, VRE, Pseudomonas aeruginosa, Candida. Wound healing: 30-50% faster closure. Overhage J et al. — Biofilm disruption against Pseudomonas aeruginosa.

What are the limits of this evidence?

The research described concerns the cited experimental materials and models, not proof that this supplied vial is a treatment. Cell or animal findings do not establish human benefits. Clinical findings, where cited, apply to the tested formulation and population; they do not validate this research product for human use.

Study references

1. Vandamme D et al. Cell Immunol 2012

These are the catalog's existing bibliographic references. No new source verification is implied by this presentation.

How should I check lot documentation?

Match the product, strength and lot to an original analysis document. Literature describes experimental findings; it does not verify the contents of this inventory. Generated sample reports illustrate the reporting flow and are not evidence of testing, purity or accreditation.