IGF-1 DES (1mg)
IGF-1 DES — Truncated IGF-1 Analog Research
Order IGF-1 DES (1mg) online for laboratory research. Compare the listed vial options and current price, then add your selection to cart and continue to checkout. Review available COA records for the exact product, strength and lot. Research Use Only; not for human or veterinary use.
IGF-1 DES is listed for growth factors laboratory research. Catalog vial contents are 1mg; select the required strength before ordering. This material is supplied for Research Use Only, not as a medicine or a product for human or veterinary use.
Research Applications & Benefits
- Des(1-3) construct research
- IGF-binding-protein comparisons
- IGF-receptor assay applications
What is IGF-1 DES?
IGF-1 DES, also called Des(1-3) IGF-I, is a truncated IGF-1 research analog lacking the first three amino acids of mature IGF-1. This catalog lists a 1mg research vial.
Listed vial contents: 1mg. These are supplied quantities, not administration doses. Current pricing and availability are shown in the strength selector.
Which identity should I verify?
Verify the Des(1-3) truncation, expected intact mass and supplied quantity in an original matching lot document. Do not treat evidence for IGF-1 LR3 or native IGF-1 as direct evidence for this construct.
What mechanisms are being studied?
Des(1-3) IGF-I has lower affinity for several IGF-binding proteins than native IGF-I. Researchers use that distinction to investigate how binding proteins regulate receptor exposure and biological responses. It is a different construct from IGF-1 LR3.
What are the research questions?
- IGF-binding-protein interactions
- IGF-receptor responses in cell and animal models
- Construct-matched comparisons with native IGF-1 and IGF-1 LR3
What does the published work describe?
Ballard and colleagues reviewed the biochemical and biological properties of Des(1-3) IGF-I. A later animal study compared IGF analogs that bind poorly to binding proteins. These findings support construct-specific research questions, not a universal potency multiplier or a treatment claim for this vial.
Experimental models in the cited papers
- Biochemical and biological literature review
- Pig and marmoset: comparative IGF-analog study
What could future research explore?
Matched assays could compare native IGF-1, Des(1-3) IGF-I and long-R3 IGF-I while controlling concentration, binding proteins and receptor system. Analytical identity should be established before interpreting those comparisons.
These are research directions, not established applications of the product sold here.
What are the limits of this evidence?
Review and animal evidence do not verify this inventory or establish human effectiveness or safety. The page does not claim a fixed ten-fold potency, localized action or a specific half-life because those statements vary by model and are not lot evidence.
Study references
- Ballard FJ, et al. Des(1-3)IGF-I: a truncated form of insulin-like growth factor-I. Int J Biochem Cell Biol. 1996. PMID 8930132
- Tomas FM, et al. IGF-I variants which bind poorly to IGF-binding proteins show more potent and prolonged hypoglycaemic action than native IGF-I in pigs and marmoset monkeys. J Endocrinol. 1997. PMID 9415072
How should I check lot documentation?
Match the product, strength and lot to an original analysis document. Literature describes experimental findings; it does not verify the contents of this inventory. A report is evidence only for the product, strength and lot it names.
How is IGF-1 DES handled in the lab?
For IGF-1 DES, record the product code IGF1DES, selected strength and lot before opening. Follow the material-specific safety data sheet and laboratory SOP, with appropriate gloves, eye protection and containment. For a documented dry preparation, let the sealed vial equilibrate before opening to reduce condensation; minimize time open and use clean, compatible vessels.
For IGF-1 DES, establish the supplied preparation or construct, formulation and activity documentation before dilution. Protein folding, aggregation, adsorption and excipient compatibility can affect assays. Evaluate compatible vessels and buffer conditions in a small study; do not add a carrier protein unless it is appropriate for the assay and documented in the SOP.
For IGF-1 DES, calculate mass concentration as measured material mass divided by final solution volume. Calculate molarity only with a documented molecular weight for the supplied chemical form; no usable molecular weight is established by the blank catalog field. Where available, use matched-lot net content rather than treating chromatographic purity as a mass correction. Record both stock concentration and subsequent dilution factors.
Use the documented storage conditions for the supplied IGF-1 DES form and lot. For a documented lyophilized preparation, keep the vial sealed and protected from moisture; for solutions, validate temperature, light exposure and holding time in the assay. Use compatible single-use aliquots when appropriate to reduce repeated freeze-thaw. No universal temperature or 28-day solution shelf life is established by the catalog name.
A IGF-1 DES laboratory protocol should record identity, product code IGF1DES, strength, lot, applicable analysis results, solvent and pH, stock concentration, dilution sequence, vessel type, storage history and assay endpoints. Include vehicle and reference controls, independent replicates and predefined acceptance criteria. Separate handling validation from biological interpretation; these notes do not provide administration or dosing instructions.
Research Use Only. Not for human consumption, therapeutic, veterinary or any in-vivo use.
Product Specifications
- Compound
- IGF-1 DES
- CAS Number
- 112603-35-7
- Molecular Weight
- HPLC Purity Specification
- ≥98%
- Category
- Growth Factors
- Starting Price
- $69.00 USD
- Country of Origin
- United States
- Shipping
- Cold-chain insulated packaging, fast domestic delivery
- Payment
- Card, ACH, and cryptocurrency (10% discount)
Quality & Verification
IGF-1 DES has a catalog purity specification of ≥98%; this is not a measured result for every vial. Match the product, exact strength, batch and lot to its analysis record and read only the reported fields. HPLC peak-area purity, measured content and endotoxin are separate measurements. A blank field means no result is reported, not zero or passed. A purity percentage alone does not establish identity, sterility or suitability for human use.
Frequently Asked Questions
What is IGF-1 DES?
IGF-1 DES is listed for growth factors laboratory research. Catalog vial contents are 1mg; select the required strength before ordering. This material is supplied for Research Use Only, not as a medicine or a product for human or veterinary use.
What strengths of IGF-1 DES are available?
The catalog lists 1mg. These labels describe vial contents, not administration doses. Select the required strength for current pricing and availability; match analysis records to that exact strength and lot.
How should I interpret IGF-1 DES purity results?
IGF-1 DES has a catalog purity specification of ≥98%; this is not a measured result for every vial. Match the product, exact strength, batch and lot to its analysis record and read only the reported fields. HPLC peak-area purity, measured content and endotoxin are separate measurements. A blank field means no result is reported, not zero or passed. A purity percentage alone does not establish identity, sterility or suitability for human use.
How should IGF-1 DES be handled in the laboratory?
For IGF-1 DES, record the product code IGF1DES, selected strength and lot before opening. Follow the material-specific safety data sheet and laboratory SOP, with appropriate gloves, eye protection and containment. For a documented dry preparation, let the sealed vial equilibrate before opening to reduce condensation; minimize time open and use clean, compatible vessels.
How do I choose a laboratory solvent for IGF-1 DES?
For IGF-1 DES, establish the supplied preparation or construct, formulation and activity documentation before dilution. Protein folding, aggregation, adsorption and excipient compatibility can affect assays. Evaluate compatible vessels and buffer conditions in a small study; do not add a carrier protein unless it is appropriate for the assay and documented in the SOP.
How do I calculate a IGF-1 DES stock concentration?
For IGF-1 DES, calculate mass concentration as measured material mass divided by final solution volume. Calculate molarity only with a documented molecular weight for the supplied chemical form; no usable molecular weight is established by the blank catalog field. Where available, use matched-lot net content rather than treating chromatographic purity as a mass correction. Record both stock concentration and subsequent dilution factors.
How should IGF-1 DES be stored after preparation?
Use the documented storage conditions for the supplied IGF-1 DES form and lot. For a documented lyophilized preparation, keep the vial sealed and protected from moisture; for solutions, validate temperature, light exposure and holding time in the assay. Use compatible single-use aliquots when appropriate to reduce repeated freeze-thaw. No universal temperature or 28-day solution shelf life is established by the catalog name.
What should a IGF-1 DES lab protocol document?
A IGF-1 DES laboratory protocol should record identity, product code IGF1DES, strength, lot, applicable analysis results, solvent and pH, stock concentration, dilution sequence, vessel type, storage history and assay endpoints. Include vehicle and reference controls, independent replicates and predefined acceptance criteria. Separate handling validation from biological interpretation; these notes do not provide administration or dosing instructions.
Does Fmoc or Boc synthesis explain this IGF-1 DES product?
The catalog name IGF-1 DES alone does not establish a synthetic, recombinant or preparation-specific production route. Confirm construct or preparation documentation and relevant analytical or activity methods before drawing conclusions from a peptide synthesis guide.
Is IGF-1 DES for human use?
No. IGF-1 DES is strictly Research Use Only. It is not intended for human or veterinary use, diagnosis or treatment. Laboratory handling guidance is not an administration protocol.
Research Use Only. This product is intended for licensed laboratory research and is not for human or veterinary use.
