Selank Peptide: the tuftsin-derived heptapeptide
Selank peptide is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) built from the immune peptide tuftsin with a Pro-Gly-Pro tail added for stability. It was developed in Russia as an anxiolytic research compound, and a published clinical study reports on its use in generalised anxiety disorders and neurasthenia (Zozulia et al., 2008). Researchers looking to buy selank for laboratory work can find ≥98% purity, HPLC-tested vials here — research use only.
Specifications
| Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro (7 amino acids) |
|---|---|
| Origin | Tuftsin analog with C-terminal Pro-Gly-Pro |
| CAS number | 129954-34-3 |
| Purity | ≥98% (HPLC) |
| Form | Lyophilised powder |
What is selank?
Selank is a synthetic analog of tuftsin, a natural tetrapeptide involved in immune signalling. Russian researchers extended tuftsin with a Pro-Gly-Pro sequence to improve metabolic stability, producing the seven-amino-acid peptide now studied under the name selank.
It is classified as an anxiolytic research peptide and is frequently compared with Semax, another Russian-developed peptide with a different structure and research focus.
Published research
A clinical study in patients with generalised anxiety disorders and neurasthenia reported on selank's efficacy and possible mechanisms of action (Zozulia et al., 2008).
In a rodent study, selank administration changed the expression of genes involved in GABAergic neurotransmission, pointing to a possible mechanism for its anxiolytic-like effects in animal models (Volkova et al., 2016).
Selank vs Semax
Both are short synthetic peptides developed in Russia, but they come from different parent molecules. Selank derives from the immune peptide tuftsin and is studied mainly in anxiety-related models; Semax derives from the ACTH(4-10) fragment and is studied mainly in cognitive and stress models. See the Semax vs Selank comparison for a side-by-side view.
Frequently asked questions
What is selank peptide?
A synthetic seven-amino-acid peptide derived from tuftsin, studied in anxiety-related research models. A published clinical study reports on its use in generalised anxiety disorders and neurasthenia.
What is the difference between selank and semax?
Selank is a tuftsin-derived heptapeptide studied in anxiety models; Semax is an ACTH(4-10)-derived heptapeptide studied in cognitive and stress models.
Is selank an approved drug?
No. Selank is not an approved medicine in the United States and is sold here strictly for laboratory research.
Where can I buy selank peptide for research?
PeptidesDirect sells selank in 10mg vials for laboratory research only. Orders placed before 1:00 PM Central on business days ship the same day. See our research peptides guide (/learn/research-peptides) for how to compare suppliers and read test documents.
How should selank be stored?
Keep lyophilised selank cold, dry and away from light; refrigerate reconstituted solutions. See our research peptides guide (/learn/research-peptides) for how to compare suppliers and read test documents.
Is this product for human use?
No. PeptidesDirect sells this compound for laboratory research only. It is not a drug, food or cosmetic and is not for human or veterinary use. This page summarises published research and is not dosing or medical guidance.
References
- Zozulia AA, et al. Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia. Zh Nevrol Psikhiatr Im S S Korsakova. 2008. PubMed 18454096
- Volkova A, et al. Selank administration affects the expression of some genes involved in GABAergic neurotransmission. Front Pharmacol. 2016. PubMed 26924987
Research compounds
Related guides
Research Use Only. Not for human or veterinary use. Not dosing or medical guidance.
